New avobenzone derivatives with improved photostability under sunlight/UV radiation: Experimental, formulation and computational studies
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Date
2025-04-20
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Department of Chemistry, School of Chemical Sciences, Central University of Karnataka
Abstract
Avobenzone is the most widely used chemical UVA filter in many sunscreen formulations to combat the harmful effects of UVA radiation [1–4]. An important drawback of avobenzone is the photounstability under sunlight/ UV radiations [5,6]. Two independent approaches have been employed to overcome these drawbacks: (i) addition of an external photostabilizers [7,8], (ii) and skeleton structure modification [9,10]. The current thesis has explored both the approaches and also peptides as a photostabilizers of avobenzone. The thesis has been organized into eight chapters: Chapter-1 provides the introduction in the context of the thesis. Chapter-2 to Chapter-7 provides specific attempts to improve the photostability of avobenzone, and Chapter-8 provides the summary and conclusion of the thesis work.